| CODE | MLS1001 | ||||||||||||
| TITLE | Introduction to Biomedical Biochemistry and Cell Biology | ||||||||||||
| UM LEVEL | 01 - Year 1 in Modular Undergraduate Course | ||||||||||||
| MQF LEVEL | 5 | ||||||||||||
| ECTS CREDITS | 6 | ||||||||||||
| DEPARTMENT | Applied Biomedical Science | ||||||||||||
| DESCRIPTION | This is a theory-based study unit on biochemistry and cell biology. The key principles of the organization and operation of the human body at the biochemical and cellular levels are covered in this study unit. This study unit consists of 3 parts: Biomedical Biochemistry, Cell Biology and Metabolism Study-Unit Aims: To enable students to recall and demonstrate knowledge of the principles of biochemistry and metabolism as applied to the biomedical field, and the basics of cell biology. Content: (Biomedical Biochemistry) Water Amino acids and proteins Carbohydrates Nucleosides, nucleotides and nucleic acids Lipids and membranes General properties of proteins Protein purification Methods of analysis of proteins Haemoglobin Myoglobin Lipoproteins Enzymes Learning Outcomes (Biomedical Biochemistry) By the end of this study-unit the students should be able to: - Define the structure of the different macromolecules; - Discuss enzyme mechanisms and kinetics; and - Outline the structure and function of haemoglobin and myoglobin. Reading List: - Berg JM, Tymoczko JL, Gatto GJ & Stryer L. Biochemistry (8th Edition), 2015. W.H. Freeman & Co. Ltd. (ISBN 1464126100). - Voet D & Voet JG. Biochemistry (4th Edition), 2010. John Wiley & Sons, Inc. (ISBN 0470917458). Content: (Cell Biology) Introduction to Cell Biology and to the techniques used to investigate the cell Comparison of Prokaryotic and Eukaryotic cell structure The plasma membrane Cell junctions The bacterial cell wall The nucleus The mitochondrion Ribosomes, endoplasmic reticulum and Golgi The cytoskeleton Learning Outcomes (Cell Biology) By the end of this study-unit the students should be able to: - Identify what technique should be used to study specific aspects of cell biology; - Recognize and draw the components of a cell; - Describe the structure of the cell components in detail; - Explain the function of each cell component; - Relate the structure of each cell component to its role in the cell; and - Perceive the role of a cell and its components within the context of a multicellular organism. Reading List: (Cell Biology) - Lodish H, Berk A, Kaiser CA, Kreiger M, Bretscher A, Ploegh H, Amon A & Martin K. Molecular Cell Biology (8th Edition), 2016. W.A. Freeman & Co (ISBN 1464183392). - Cooper GM & Hausman RE. The Cell: A Molecular Approach (7th Edition), 2015. Sinauer Associates Inc. (ISBN 1605352909). Content: (Metabolism) - Introduction to metabolism, vitamins and co-‐enzymes - Glycolysis - Citric acid cycle - Oxidative phosphorylation - Pentose phosphate pathway - Phosphate pathway Gluconeogenesis Glycogen metabolism - Fatty acid metabolism Amino acid degradation - Biosynthesis of amino acids Biosynthesis of lipids - Biosynthesis of nucleotides - metabolism Learning Outcomes (Metabolism) By the end of this study-unit the students should be able to: - Recall how energy is derived from the breakdown of the major food constituents; - Relate how enzyme malfunction in metabolic pathways results in disease; - Discuss the synthesis of macromolecules; and - Demonstrate the integration of metabolism. Reading List: (Metabolism) - Berg JM, Tymoczko JL, Gatto GJ & Stryer L. Biochemistry (8th Edition), 2015. W.H. Freeman & Co. Ltd. (ISBN 1464126100). - Voet D & Voet JG. Biochemistry (4th Edition), 2010. John Wiley & Sons, Inc. (ISBN 978-0-470-91410-6). |
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| STUDY-UNIT TYPE | Lecture | ||||||||||||
| METHOD OF ASSESSMENT |
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| LECTURER/S | Joseph Borg Laura Grech David Saliba |
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The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2024/5. It may be subject to change in subsequent years. |
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