Study-Unit Description

Study-Unit Description


CODE MLS2018

 
TITLE Haematopathology

 
UM LEVEL 02 - Years 2, 3 in Modular Undergraduate Course

 
MQF LEVEL 5

 
ECTS CREDITS 3

 
DEPARTMENT Applied Biomedical Science

 
DESCRIPTION This is a structured lecture-based study-unit consisting of two sections. Section A (Normal Blood Physiology) highlights fundamental basic pathophysiological concepts relating to blood function and necessary for the understanding of blood pathology, whilst Section B (Haematopathology) is a discussion of the individual blood disorders/group of haematological conditions focusing primarily on the nature of these conditions rather than diagnosis which will be the subject of discussion in MLS2019. Students will have up to 3 x 1–hour lecture sessions per week to discuss this study-unit.

Content:

Section A – Normal Blood Physiology
• Introduction to haematology
• Haematopoiesis
• Red cell structure & function
• Normal haemostasis

Section B – Haematopathology
• The anaemias & their classification. Iron deficiency
• Macrocytic anaemias
• Congenital & acquired haemolytic anaemias
• Leucocytes structure and function
• White cell disorders – benign conditions
• Platelets structure and function
• The Acute leukaemias
• The Chronic Leukaemias
• The myelodysplastic syndromes
• Hodgkin’s and Non-Hodgkin’s Lymphomas
• Multiple myeloma & Paraproteinaemias
• Chronic myeloproliferative neoplasms
• Congenital & acquired coagulation disorders including disseminated intravascular coagulation
• Thrombotic disease and antithrombotic therapy
• Haematological disorders in systemic disease
• Basic principles of stem cell transplantation in haematology

Learning Outcomes

By the end of this study-unit, students should be able to:
• Describe the basic pathophysiological principles necessary for the understanding of the various blood disorders;
• Classify haematological disease;
• Discuss the various individual conditions or group of disorders that affect the haematological system; and
• Formulate a list of appropriate diagnostic parameters which will be dealt with in greater detail in study-unit MLS2019.

Reading List:

• Hoffbrand V & Moss Paul AH. Hoffbrand's Essential Haematology, 7th Edition. 2016, Wiley-Blackwell ISBN : 978-1-118-40866-7
• Pallister CJ & Watson M. Haematology, 2nd Revised edition. 2010, Scion Publishing Ltd, Bloxham. ISBN-13: 978-1-904-84239-2
• Swerdlow SJ, Campo E, Harris NL, Jaffe ES, Pieri SA, Stein H, Thiele J, Vardiman JW. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues Revised 4th Edition. 2017, WHO publishers. ISBN 9789283244943 (NLM Classification: WH-15)

 
STUDY-UNIT TYPE Lecture

 
METHOD OF ASSESSMENT
Assessment Component/s Assessment Due Sept. Asst Session Weighting
Examination (2 Hours) SEM1 Yes 100%

 
LECTURER/S Joseph Borg
Patricia Brincat
Rosienne Farrugia
Alexander Gatt

 

 
The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints.
Units not attracting a sufficient number of registrations may be withdrawn without notice.
It should be noted that all the information in the description above applies to study-units available during the academic year 2024/5. It may be subject to change in subsequent years.

https://www.um.edu.mt/course/studyunit