| CODE | MLS3001 | ||||||||
| TITLE | Transfusion Medicine | ||||||||
| UM LEVEL | 03 - Years 2, 3, 4 in Modular Undergraduate Course | ||||||||
| MQF LEVEL | 6 | ||||||||
| ECTS CREDITS | 6 | ||||||||
| DEPARTMENT | Applied Biomedical Science | ||||||||
| DESCRIPTION | Objectives: This study-unit provides the student with the necessary theoretical knowledge underlying the basic clinical concepts and analytical procedures in the area of Transfusion Medicine. Knowledge on Antigen-Antibody reactions and the Complement system are a prerequisite for this module. Content - Part I: Subject Overview and Introduction to Blood Transfusion General Immunohaematology Basic Red Cells Serology Techniques The ABO blood Group System The Rh Blood Group System Major Blood Group Systems ABO and Rh Typing Blood Donation Preparation of Blood Components Monitoring the Quality of Blood Components Transfusion Transmitted Infections Testing For Transfusion Transmitted Infections. Content (Part II): Antibody Screening and Identification Antibody Identification case studies The Anti-Human Globulin Test Investigation of a Positive Direct Antiglobulin Test Red Cell acid elution technique Pre-Transfusion testing and the selection of blood products Haemovigilance and Traceability Investigation of Transfusion Reactions Haemolytic Disease of the Foetus and Newborns Laboratory Tesing during pregnancy and after delivery Autoimmune Haemolytic Anaemias Techniques for the laboratory investigations of AIHA Adsorption techniques Optimal use of blood components. Learning Outcomes: By the end of the study-unit the student should be able to: • Discuss the selection, component preparation and testing of donor blood; • Discuss in detail aspects of the ABO, Rh, and other major blood group systems; • Describe pre‐transfusion testing and outline the different tests and techniques used to ensure compatible blood is available for the patient; • Review the blood group serology tests used in pretransfusion testing and antenatal testing; and • Discuss optimal use of blood components. Reading List: • Geoff Daniels, Imelda Bromilow. Essential Guide to Blood Group, 3rd ed. October 2013, Wiley-Blackwell. ISBN: 978-1-118-68892-2 • Harmening DM. Modern Blood Banking & Transfusion Practices, 7th ed. Philadelphia: F.A. Davis Company, 2018. ISBN-13: 978-0803668881 • Knight R. Fundamentals of Biomedical Science Blood Transfusion and Transplantation, 2nd edition, Oxford University Press 2018. ISBN: 9780198735731 • Klein, Harvey G. Anstee, David J.; Mollison P.L. Mollison's blood transfusion in clinical medicine. - 12th rev. ed. Blackwell Publishing 2014. ISBN: 978-1-405-19940-7 • Overfield J, Dawson M, Hamer D. Transfusion Science (Biomedical Science Explained Series), 2nd Edition. 2008, Scion Publishing Ltd. ISBN 978-1-904842-40-8 • Screening donated blood for transfusion-transmissible infections: recommendations. World Health Organization 2010. ISBN 978 92 4 154788 8. Web Resources • British Committee for Standards in Haematology. GUIDELINE FOR BLOOD GROUPING AND RED CELL ANTIBODY TESTING IN PREGNANCY. Available from: https://onlinelibrary.wiley.com/doi/epdf/10.1111/tme.12299 • British Committee for Standards in Haematology. Guidelines for pre-transfusion compatibility procedures in blood transfusion laboratories. Available from: http://onlinelibrary.wiley.com/doi/10.1111/j.1365-3148.2012.01199.x/pdf • Serious Hazards of Transfusion website. Available at: http://www.shotuk.org/ • Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee. Guidelines for the Blood Transfusion Services in the UK 8th Edition. Available at: www.transfusionguidelines.org.uk/red-book • National Blood Transfusion Service website. Available at: https://healthservices.gov.mt/en/nbts/Pages/home.aspx • Medicines authority website. Available at: http://medicinesauthority.gov.mt/blood • Council of Europe website. Available at: http://www.coe.int/web/portal/home |
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| STUDY-UNIT TYPE | Lecture | ||||||||
| METHOD OF ASSESSMENT |
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| LECTURER/S | Monique Angele Abela Jesmond Debono Antonella Giordmaina Stefan Laspina Vanessa Zammit |
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The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2024/5. It may be subject to change in subsequent years. |
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