| CODE | PHR2443 | ||||||||||||
| TITLE | Applied Pharmaceutical Biochemistry | ||||||||||||
| UM LEVEL | 02 - Years 2, 3 in Modular Undergraduate Course | ||||||||||||
| MQF LEVEL | 5 | ||||||||||||
| ECTS CREDITS | 5 | ||||||||||||
| DEPARTMENT | Pharmacy | ||||||||||||
| DESCRIPTION | As pharmacy education is being re-dimensioned internationally to adopt an integrated and applied approach to include basic concepts within pharmaceutical aspects, this study unit provides an application dimension of biochemistry as it relates to pharmacy practice. The study-unit presents a pharmaceutical focus to aspects related to a) structure and function of proteins, lipids, carbohydrates and how these relate to drugs, toxicology and clinical enzymology b) endocrine control pathways and aspects of pharmacist-led point-of-care diagnostics relevant for patient monitoring and c) optimisation of pharmacotherapy in human diseases (cancer, cardiovascular, psychiatry) based on an understanding of biochemical pathways including signal transduction and the contribution to support pharmacogenetics and precision medicine.The study-unit includes practical laboratory sessions to support the understanding and development of skills in applications of clinical biochemistry and application of point-of-care testing. Study-Unit Aims: The study-unit aims to provide students with application of fundamental knowledge of biochemical processes as it impacts research and development of advanced therapies, use of medicines in the management of disease states, optimization of rational selection in individualization of therapy and patient monitoring. Learning Outcomes: 1. Knowledge & Understanding: By the end of the study-unit the student will be able to: - describe biochemical pathways that affect drug use, toxicology implications and optimization of therapy; - describe flow of genetic information and general mechanisms of gene regulation as they relate to choice of treatment; - extrapolate causes of diseases and effects of drugs and critically approach development of new modes of treatment. 2. Skills: By the end of the study-unit the student will be able to: - apply biochemical knowledge to rational selection of medicines and to principles of formulation development; - formulate care plans associated with pharmacotherapy including relevant patient monitoring of biological parameters; - apply biochemical knowledge to point-of-care testingto appraise point-of-care testing devices and support patients to use patient self-testing devices; - perform point-of-care testing and provide counselling and clinical decisions within a collaborative care model. Main Text/s and any supplementary readings: Main Texts: - Woodbury CP. Biochemistry for the pharmaceutical sciences. Jones & Bartlett Learning 2012. - Murphy M et al. Clinical Biochemistry. Elsevier, 2018. Supplementary Readings: - Ronner P. Netter's Essential Biochemistry. Elsevier, 2017. - Baynes J & Dominiczak M, Medical Biochemistry. Elsevier, 2018. |
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| ADDITIONAL NOTES | Please note that a pass in the Practical component is obligatory for an overall pass mark to be awarded. | ||||||||||||
| STUDY-UNIT TYPE | Lecture and Practical | ||||||||||||
| METHOD OF ASSESSMENT |
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| LECTURER/S | Lilian M. Azzopardi Sephorah Falzon Marise Gauci Louise Grech Maresca Attard Pizzuto Anthony Serracino Inglott Francesca Wirth |
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The University makes every effort to ensure that the published Courses Plans, Programmes of Study and Study-Unit information are complete and up-to-date at the time of publication. The University reserves the right to make changes in case errors are detected after publication.
The availability of optional units may be subject to timetabling constraints. Units not attracting a sufficient number of registrations may be withdrawn without notice. It should be noted that all the information in the description above applies to study-units available during the academic year 2024/5. It may be subject to change in subsequent years. |
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