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Title: | Neuropsychological study of IQ scores in offspring of parents with bipolar I disorder |
Authors: | Sharma, Aditya Camilleri, Nigel Grunze, Heinz Barron, Evelyn Le Couteur, James Close, Andrew Rushton, Steven Kelly, Thomas Ferrier, Ian Nicol Le Couteur, Ann |
Keywords: | Manic-depressive illness Intelligence levels Mental health Mental illness Neurodevelopmental disorders |
Issue Date: | 2016 |
Publisher: | Routledge |
Citation: | Sharma, A., Camilleri, N., Grunze, H., Barron, E., Le Couteur, J., Close, A., ... & Le Couteur, A. (2017). Neuropsychological study of IQ scores in offspring of parents with bipolar I disorder. Cognitive Neuropsychiatry, 22(1), 17-27. |
Abstract: | Introduction: Studies comparing IQ in Offspring of Bipolar Parents (OBP) with Offspring of Healthy Controls (OHC) have reported conflicting findings. They have included OBP with mental health/ neurodevelopmental disorders and/or pharmacological treatment which could affect results. This UK study aimed to assess IQ in OBP with no mental health/neurodevelopmental disorder and assess the relationship of sociodemographic variables with IQ. Methods: IQ data using the Wechsler Abbreviated Scale of Intelligence (WASI) from 24 OBP and 34 OHC from the North East of England was analysed using mixed-effects modelling. Results: All participants had IQ in the average range. OBP differed statistically significantly from OHC on Full Scale IQ (p = .001), Performance IQ (PIQ) (p = .003) and Verbal IQ (VIQ) (p = .001) but not on the PIQ-VIQ split. OBP and OHC groups did not differ on socio-economic status (SES) and gender. SES made a statistically significant contribution to the variance of IQ scores (p = .001). Conclusions: Using a robust statistical model of analysis, the OBP with no current/past history of mental health/neurodevelopmental disorders had lower IQ scores compared to OHC. This finding should be borne in mind when assessing and recommending interventions for OBP. |
URI: | https://www.um.edu.mt/library/oar//handle/123456789/22387 |
Appears in Collections: | Scholarly Works - FacM&SPsy |
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