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DC Field | Value | Language |
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dc.contributor.author | Cope, Henry | - |
dc.contributor.author | Willis, Craig R. G. | - |
dc.contributor.author | MacKay, Matthew J. | - |
dc.contributor.author | Rutter, Lindsay A. | - |
dc.contributor.author | Toh, Li Shean | - |
dc.contributor.author | Williams, Philip M. | - |
dc.contributor.author | Herranz, Raul | - |
dc.contributor.author | Borg, Joseph J. | - |
dc.contributor.author | Bezdan, Daniela | - |
dc.contributor.author | Giacomello, Stefania | - |
dc.contributor.author | Muratani, Masafumi | - |
dc.contributor.author | Mason, Christopher E. | - |
dc.contributor.author | Etheridge, Timothy | - |
dc.contributor.author | Szewczyk, Nathaniel J. | - |
dc.date.accessioned | 2022-08-02T08:41:45Z | - |
dc.date.available | 2022-08-02T08:41:45Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | Cope, H., Willis, C.R.G., MacKay, M.J., Rutter, L.A., Toh, L.S., Williams, P.M…. Szewczyk, N.J. (2022). Routine omics collection is a golden opportunity for European human research in space and analog environments. Patterns, 3, 1-16 | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/100200 | - |
dc.description.abstract | Widespread generation and analysis of omics data have revolutionized molecular medicine on Earth, yet its power to yield new mechanistic insights and improve occupational health during spaceflight is still to be fully realized in humans. Nevertheless, rapid technological advancements and ever-regular spaceflight programs mean that longitudinal, standardized, and cost-effective collection of human space omics data are firmly within reach. Here, we consider the practicality and scientific return of different sampling methods and omic types in the context of human spaceflight. We also appraise ethical and legal considerations pertinent to omics data derived from European astronauts and spaceflight participants (SFPs). Ultimately, we propose that a routine omics collection program in spaceflight and analog environments presents a golden opportunity. Unlocking this bright future of artificial intelligence (AI)-driven analyses and personalized medicine approaches will require further investigation into best practices, including policy design and standardization of omics data, metadata, and sampling methods. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Cell Press | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Space flight -- Computer simulation | en_GB |
dc.subject | Personalized medicine -- Economic aspects | en_GB |
dc.subject | International Space Station | en_GB |
dc.subject | Space stations -- International cooperation | en_GB |
dc.subject | Longitudinal method | en_GB |
dc.subject | Data protection -- Law and legislation | en_GB |
dc.subject | Astronauts | en_GB |
dc.subject | Biobanks | en_GB |
dc.subject | Artificial intelligence -- Case studies | en_GB |
dc.title | Routine omics collection is a golden opportunity for European human research in space and analog environments | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.identifier.doi | 10.1016/j.patter.2022.100550 | - |
dc.publication.title | Patterns | en_GB |
Appears in Collections: | Scholarly Works - FacHScABS |
Files in This Item:
File | Description | Size | Format | |
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Routine_omics_collection_is_a_golden_opportunity_for_European_human_research_in_space_and_analog_environments.pdf | 1.31 MB | Adobe PDF | View/Open |
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