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Title: | Does baseline hemoglobin A 1c level predict diabetic foot ulcer outcome or wound healing time? |
Authors: | Vella, Lourdes Gatt, Alfred Formosa, Cynthia |
Keywords: | Foot -- Ulcers -- Treatment Hemoglobin A -- Therapeutic use Type 2 diabetes Foot -- Ulcers -- Malta -- Case studies Diabetes -- Complications |
Issue Date: | 2017 |
Publisher: | American Podiatric Medical Association |
Citation: | Vella, L., Gatt, A., & Formosa, C. (2017). Does baseline hemoglobin A1c level predict diabetic foot ulcer outcome or wound healing time?. Journal of the American Podiatric Medical Association, 107(4), 272-279. |
Abstract: | Background: We sought to evaluate the relationship between baseline hemoglobin A1c
(HbA1c) level and clinical outcomes, including foot ulcer outcome (resolved versus
unresolved) and wound-healing time, in individuals with type 2 diabetes. Methods: A prospective observational study was conducted on 99 patients presenting with a diabetic foot ulceration. Patient and ulcer characteristics were recorded. Patients were followed up for a maximum of 1 year. Results: After 1 year of follow-up, 77% of ulcers healed and 23% did not heal. Although this study demonstrated that the baseline HbA1c reading was not a significant predictor of foot ulcer outcome ( P .603, resolved versus amputated), on further statistical analyses, when HbA1c was compared with the time taken for complete ulcer healing in the resolved group (n = 77), it proved to be significant (P = .009). Conclusions: These findings have important implications for clinical practice, especially in an outpatient setting. Improving glycemic control may improve ulcer outcomes. Prediction of outcome may be helpful for health-care professionals in individualizing and optimizing clinical assessment and management of patients. Identification of determinants of outcome could result in improved health outcomes, improved quality of life, and fewer diabetes-related foot complications. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/100291 |
Appears in Collections: | Scholarly Works - FacHScPod |
Files in This Item:
File | Description | Size | Format | |
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Does baseline hemoglobin A 1c level predict diabetic foot ulcer outcome or wound healing time.pdf Restricted Access | 4.99 MB | Adobe PDF | View/Open Request a copy |
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