Effects of intermittent calf muscle electrical stimulation on walking capacity in claudicants living with type 2 diabetes

Abstract

Background: First-line therapy for diabetic patients presenting with intermittent claudication includes supervised exercise programs to improve walking distance. However, exercise comes with a variety of barriers and may be contraindicated in certain conditions. The aim of this study was to evaluate whether calf muscle electrostimulation improves claudication distance. Methods: A prospective, one-group, pretest-posttest study design was used on 40 participants living with type 2 diabetes mellitus, peripheral artery disease (ankle brachial pressure index, ,0.90), and calf muscle claudication. Calf muscle electrostimulation of varying frequencies (1–250 Hz) was prescribed on both limbs for 1-hour daily sessions for 12 consecutive weeks. The absolute claudication distance (ACD) was measured at baseline and after the intervention. Results: The recruited cohort (30 men and ten women; mean age, 71 years; mean ankle brachial pressure index, 0.70) registered a mean 6 SD baseline ACD of 333.71 6 208 m. After a mean 6 SD of 91.68 6 6.23 days of electrical stimulation, a significant mean 6 SD increase of 137 6 136 m in the ACD (P¼.001, Wilcoxon signed rank test) was registered. Improvement was found to be sex independent, but age was negatively correlated with proportion of improvement (r ¼ –0.361; P ¼ .011, Pearson correlation test). Conclusions: Electrical stimulation of varying frequencies on ischemic calf muscles significantly increased the maximal walking capacity in claudicants with type 2 diabetes. This therapeutic approach should be considered in patients with impaired exercise tolerance or as an adjunct treatment modality. (J Am Podiatr Med Assoc 110(1): 1-7, 2020)