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DC Field | Value | Language |
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dc.contributor.author | Adriaenssens, Niels | - |
dc.contributor.author | Coenen, Samuel | - |
dc.contributor.author | Versporten, Ann | - |
dc.contributor.author | Muller, Arno | - |
dc.contributor.author | Minalu, Girma | - |
dc.contributor.author | Faes, Christel | - |
dc.contributor.author | Vankerckhoven, Vanessa | - |
dc.contributor.author | Aerts, Marc | - |
dc.contributor.author | Hens, Niel | - |
dc.contributor.author | Molenberghs, Geert | - |
dc.contributor.author | Goossens, Herman | - |
dc.contributor.author | Zarb, Peter | - |
dc.date.accessioned | 2022-09-23T07:53:35Z | - |
dc.date.available | 2022-09-23T07:53:35Z | - |
dc.date.issued | 2011 | - |
dc.identifier.citation | Adriaenssens, N., Coenen, S., Versporten, A., Muller, A., Minalu, G., Faes, C., ... & Goossens, H. (2011). European Surveillance of Antimicrobial Consumption (ESAC): outpatient antibiotic use in Europe (1997–2009). Journal of antimicrobial chemotherapy, 66(suppl_6), vi3-vi12. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/101948 | - |
dc.description.abstract | Objectives: To describe total outpatient systemic antibiotic use in Europe from 1997 to 2009 and to analyse statistically trends of total use and composition of use over time. Methods: For the period 1997–2009, data on outpatient use of systemic antibiotics aggregated at the level of the active substance were collected and expressed in defined daily doses (WHO, version 2011) and packages per 1000 inhabitants per day (DID and PID, respectively). Outpatient antibiotic (ATC J01) use in DID in the 33 European countries able to deliver valid data was analysed using longitudinal and compositional data analyses. Results: Total outpatient antibiotic use in 2009 varied by a factor of 3.8 between the countries with the highest (38.6 DID in Greece) and lowest (10.2 DID in Romania) use. For Europe, a significant increase was found in total outpatient antibiotic use, as well as a significant seasonal variation, which decreased over time from 1997 to 2009. Relative use of penicillins and quinolones significantly increased over time with respect to sulphonamides and trimethoprim, and relative use of quinolones increased with respect to macrolide/lincosamide/streptogramin as well. More detailed analyses of these major antibiotic subgroups will be described in separate papers. Conclusions: Outpatient antibiotic use in Europe measured as DID has increased since 1997, whereas seasonal variation has decreased over time. European Surveillance of Antimicrobial Consumption (ESAC) data on outpatient antibiotic use in Europe enable countries to audit their antibiotic use. Complemented by longitudinal and compositional data analyses, these data provide a tool for assessing public health strategies aimed at reducing antibiotic resistance and optimizing antibiotic prescribing. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Oxford University Press | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Drug utilization | en_GB |
dc.subject | Pharmacoepidemiology | en_GB |
dc.subject | Ambulatory medical care -- Case studies | en_GB |
dc.title | European Surveillance of Antimicrobial Consumption (ESAC) : outpatient antibiotic use in Europe (1997–2009) | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder | en_GB |
dc.contributor.corpauthor | ESAC Project Group | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.identifier.doi | 10.1093/jac/dkr453 | - |
dc.publication.title | Journal of Antimicrobial Chemotherapy | en_GB |
Appears in Collections: | Scholarly Works - FacM&SPat |
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File | Description | Size | Format | |
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European_surveillance_of_antimicrobial_consumption_2.pdf | 537.63 kB | Adobe PDF | View/Open |
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