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dc.contributor.authorBorg, Michael Angelo-
dc.contributor.authorZarb, Peter-
dc.contributor.authorFerech, Matus-
dc.contributor.authorGoossens, Herman-
dc.date.accessioned2022-09-27T10:32:07Z-
dc.date.available2022-09-27T10:32:07Z-
dc.date.issued2008-
dc.identifier.citationBorg, M. A., Zarb, P., Ferech, M., & Goossens, H. (2008). Antibiotic consumption in southern and eastern Mediterranean hospitals: results from the ARMed project. Journal of Antimicrobial Chemotherapy, 62(4), 830-836.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/102067-
dc.description.abstractObjectives: The intensity of antibiotic use in hospital settings is recognized as possibly the most important factor for the selection of antimicrobial resistance. Hospitals are therefore being encouraged to undertake surveillance and benchmarking of antimicrobial consumption patterns with a view to identify and rectify possible evidence of overuse or misuse. Methods: As part of the ARMed project, antibiotic use in 25 hospitals from the southern and eastern Mediterranean countries of Cyprus, Egypt, Jordan, Lebanon, Malta, Tunisia and Turkey was assessed prospectively for 24 months during the years 2004–05. The surveillance focused primarily on systemic antibiotics used in hospital care, aggregated at the level of the active substance, in accordance with the Anatomic Therapeutic Chemical (ATC) classification. Results: The median total antibiotic use during the study period was 112 defined daily doses per 100 bed-days (DDD/100BD), with an inter-quartile range of 84–428 DDD/100BD. The most common antibiotic groups prescribed were the extended-spectrum and combination penicillins, first- and thirdgeneration cephalosporins and quinolones. Overall, a predominant consumption of wide-spectrum agents was noted, with a significant correlation between the levels of use of third-generation cephalosporins and carbapenems. Conclusions: Emphasis on wide-spectrum agents could explain one possible factor behind the documented high prevalence of resistance in important pathogens within these same hospitals and suggests the need for improved antibiotic stewardship and prescribing programmes, which may well be applicable to the whole region.en_GB
dc.language.isoenen_GB
dc.publisherOxford University Pressen_GB
dc.rightsinfo:eu-repo/semantics/openAccessen_GB
dc.subjectPublic health surveillanceen_GB
dc.subjectCephalosporinsen_GB
dc.subjectPenicilliumen_GB
dc.titleAntibiotic consumption in southern and eastern Mediterranean hospitals: results from the ARMed projecten_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holderen_GB
dc.contributor.corpauthorARMed Project Groupen_GB
dc.description.reviewedpeer-revieweden_GB
dc.identifier.doi10.1093/jac/dkn260-
dc.publication.titleJournal of Antimicrobial Chemotherapyen_GB
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