Crohn’s disease

Abstract

44-year-old female known case of Crohn’s disease and depression who presented with a few hours’ history of severe abdominal pain and multiple episodes of vomiting faeculant matter. An inflamed terminal ileum and ascending colon were found at laparatomy and resection of terminal ileum and caecum (right hemicolectomy) was carried out. Crohn’s is a chronic inflammatory bowel disorder of unknown aetiology which can affect the whole gastrointestinal system (from mouth to anus) and is typified by asymmetric, focal, transmural inflammation and sometimes granuloma formation in the bowel wall. Signs of extraintestinal manifestation can be marked. The life-long disease is punctuated by periods of exacerbation and remission15. Genetic and environmental contributors, as well as immunological factors are implicated in the pathogenesis and severity of Crohn’s disease.