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DC Field | Value | Language |
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dc.contributor.author | Xerri, Thelma | - |
dc.contributor.author | Borg, Janice | - |
dc.contributor.author | Casha, Ramon | - |
dc.contributor.author | Fsadni, Claudia | - |
dc.date.accessioned | 2023-03-07T10:46:34Z | - |
dc.date.available | 2023-03-07T10:46:34Z | - |
dc.date.issued | 2021 | - |
dc.identifier.citation | Xerri, T., Borg, J., Casha, R., & Fsadni, C. (2021). Complexity of Mycobacterium avium complex immune reconstitution inflammatory syndrome (MAC-IRIS) in a patient with HIV. BMJ Case Reports, 14(9), e241813. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/107125 | - |
dc.description.abstract | We report a case of Mycobacterium avium complex immune reconstitution inflammatory syndrome (MAC-IRIS) in a patient with HIV positive. Initial presentation was that of a purpuric purple macular rash in-keeping with Kaposi sarcoma as an AIDS defining illness. Three weeks following the initiation of antiretroviral treatment (ART) she developed chest pain, dry cough and fever. A diagnosis of MAC was made through imaging and sputum cultures and appropriate treatment was initiated. Despite adequate management with evidence of good immunological and virological response, the patient represented with persistent symptoms. Repeat CT of the chest confirmed worsening lymphadenopathy with necrosis. Given these findings, a diagnosis of MAC-IRIS was made with resolution of fever after corticosteroids were initiated. This case highlights the importance of considering MAC as a cause of IRIS in severely immunosuppressed patients with HIV. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | BMJ Group | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Mycobacterium avium paratuberculosis -- Malta -- Case studies | en_GB |
dc.subject | Mycobacterium avium paratuberculosis -- Treatment | en_GB |
dc.subject | Immune reconstitution inflammatory syndrome | en_GB |
dc.subject | HIV-positive persons | en_GB |
dc.subject | AIDS (Disease) -- Patients | en_GB |
dc.title | Complexity of Mycobacterium avium complex immune reconstitution inflammatory syndrome (MAC-IRIS) in a patient with HIV | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.identifier.doi | 10.1136/bcr-2021-241813 | - |
dc.publication.title | BMJ Case Reports | en_GB |
Appears in Collections: | Scholarly Works - FacM&SMed |
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Complexity of Mycobacterium avium complex immune reconstitution inflammatory syndrome MAC IRIS in a patient with HIV 2021.pdf Restricted Access | 489.5 kB | Adobe PDF | View/Open Request a copy |
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