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DC Field | Value | Language |
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dc.contributor.author | Borg, Victoria | - |
dc.contributor.author | Saliba, Christian | - |
dc.contributor.author | Fenech, Anthony | - |
dc.contributor.author | Grech, Godfrey | - |
dc.date.accessioned | 2023-04-21T13:32:51Z | - |
dc.date.available | 2023-04-21T13:32:51Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Borg, V., Saliba, C., Fenech, A., & Grech, G. (2015). Stability of β-catenin as a potential mechanism of glucocorticoid dependant expansion of human erythroid progenitors. IX Malta Medical School Conference abstract book, P4.15. | en_GB |
dc.identifier.issn | 18133339 | - |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/108810 | - |
dc.description.abstract | Introduction: Cooperative signalling between the glucocorticoid nuclear receptor and the cytokine receptors was proven to be central for proper balance between progenitor proliferation and differentiation. The glucocorticoid, Dexamethasone (Dex) has been identified as an essential requirement for the generation of mass cultures of erythroblasts. The production of massive cultures of human red blood cells in vitro would possibly lead to ex vivo transfusions. Although many signalling pathways have been unravelled, transcription regulation induced by glucocorticoids in haematopoietic progenitors is still unclear. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | University of Malta. Medical School | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Erythroid precursor cells | en_GB |
dc.subject | Glucocorticoids -- Receptors | en_GB |
dc.subject | Cell differentiation -- Molecular aspects | en_GB |
dc.subject | Cell proliferation -- Molecular aspects | en_GB |
dc.title | Stability of β-catenin as a potential mechanism of glucocorticoid dependant expansion of human erythroid progenitors | en_GB |
dc.type | conferenceObject | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.bibliographicCitation.conferencename | Ninth Malta Medical School Conference | en_GB |
dc.bibliographicCitation.conferenceplace | St. Julians, Malta. 02-05/12/2015. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | Malta Medical Journal | en_GB |
Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
File | Description | Size | Format | |
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Stability of B catenin as a potential mechanism of glucocorticoid dependant expansion of human erythroid progenitors 2015.pdf | 93.27 kB | Adobe PDF | View/Open |
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