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Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/108852
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dc.contributor.authorSaliba, Christian-
dc.contributor.authorGauci, Robert-
dc.contributor.authorBaldacchino, Shawn-
dc.contributor.authorGrixti, Maria Pia-
dc.contributor.authorScerri, Christian-
dc.contributor.authorGrech, Godfrey-
dc.date.accessioned2023-04-24T16:01:11Z-
dc.date.available2023-04-24T16:01:11Z-
dc.date.issued2015-
dc.identifier.citationSaliba, C., Gauci, R., Baldacchino, S., Grixti, M.P., Scerri, C., & Grech, G. (2015). Decreased expression of CIP2A and SETBP1 following drug-induced activation of the PP2A complex in triple negative breast cancer cell lines. IX Malta Medical School Conference abstract book, P4.10.en_GB
dc.identifier.issn18133339-
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/108852-
dc.description.abstractIntroduction: Triple negative breast cancer (TNBC) patients derive little benefit from target-specific therapies due to Jack of the favourable prognostic targets. Data from the cBioPortal for Cancer Genomics demonstrate that PP2A function is likely to be reduced in up to 60% of basal breast tumours. Tumours exhibit either homozygous deletion or underexpression of PP2A, but also overexpression of PP2A inhibitors namely CIP2A, SET and/or SETBP1. In this study we assess the effect of FTY720, an activator of PP2A, on breast cancer cell lines.en_GB
dc.language.isoenen_GB
dc.publisherUniversity of Malta. Medical Schoolen_GB
dc.rightsinfo:eu-repo/semantics/openAccessen_GB
dc.subjectTriple negative breast neoplasms -- Diagnosisen_GB
dc.subjectBreast -- Cancer -- Diagnosisen_GB
dc.subjectProtein phosphatase 2en_GB
dc.subjectPhosphoprotein phosphatases -- Inhibitorsen_GB
dc.subjectFingolimod hydrochlorideen_GB
dc.titleDecreased expression of CIP2A and SETBP1 following drug-induced activation of the PP2A complex in triple negative breast cancer cell linesen_GB
dc.typeconferenceObjecten_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.bibliographicCitation.conferencenameNinth Malta Medical School Conferenceen_GB
dc.bibliographicCitation.conferenceplaceSt. Julians, Malta. 02-05/12/2015.en_GB
dc.description.reviewedpeer-revieweden_GB
dc.publication.titleMalta Medical Journalen_GB
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