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https://www.um.edu.mt/library/oar/handle/123456789/108853| Title: | Novel molecular classifiers of basal-type subset in breast cancer patients |
| Authors: | Baldacchino, Shawn Saliba, Christian Ebejer, Jean Paul DeGaetano, James Scerri, Christian Grech, Godfrey |
| Keywords: | Breast -- Cancer -- Malta -- Case studies Basal cell carcinoma Protein phosphatase 2 Phosphoprotein phosphatases -- Inhibitors Gene expression -- Analysis |
| Issue Date: | 2015 |
| Publisher: | University of Malta. Medical School |
| Citation: | Baldacchino, S., Saliba, C., Ebejer, J. P., DeGaetano, J., Scerri, C., & Grech, G. (2015). Novel molecular classifiers of basal-type subset in breast cancer patients. IX Malta Medical School Conference abstract book, OP3.15. |
| Abstract: | Introduction: The basal breast cancer subtype persists as a heterogeneous group that shows worse prognosis due to lack of targeted therapy. Understanding the deregulated cellular mechanisms uncovers new therapeutic targets which require biomarkers to select eligible patients. Analysis of datasets (cBioP01tal) show that 59.6% ofvbasal cancer exhibit deregulation of the PP2A cellular feedback mechanism. Our study aims to define biomarkers for PP2A deregulation in the basal subtype. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/108853 |
| ISSN: | 18133339 |
| Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Novel molecular classifiers of basal type subset in breast cancer patients 2015.pdf | 131.22 kB | Adobe PDF | View/Open |
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