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DC Field | Value | Language |
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dc.contributor.author | Grech, Godfrey | - |
dc.contributor.author | Scerri, Christian | - |
dc.contributor.author | Saliba, Christian | - |
dc.contributor.author | Baldacchino, Shawn | - |
dc.date.accessioned | 2023-04-26T07:34:46Z | - |
dc.date.available | 2023-04-26T07:34:46Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Grech, A, Scerri, C., Saliba, C., & Baldacchino, S. (2018). Biomarkers predicting sensitivity to PP2A activation therapy in cancer. International application published under the Patent Cooperation Treaty (PCT-EP2018-057189). International Publication WO 2018/172419 Al. | en_GB |
dc.identifier.uri | https://patents.google.com/patent/WO2018172419A1/en?oq=PCT-EP2018-057189 | - |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/108906 | - |
dc.description.abstract | The invention relates to the treatment and classification of cancer, in particular breast cancer. It relates to identifying patients who are likely to respond to cancer therapy with a PP2 A activator. Background: The provision of new treatments for cancer is of high importance, including for cancers resistant to known treatments. There is also a need for identification of markers that allow for detection, prognosis and classification of cancer, and which can predict responsiveness of a patient to a given therapy. The deregulation of the protein phosphatase 2A (PP2A) complex is known to be a common event in cancer [Grech et al; Tumor Biol; DOl 10.1007/s13277-016-5145-4 (2016)]. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Patent Cooperation Treaty (PCT) | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Breast -- Cancer -- Classification | en_GB |
dc.subject | Breast -- Cancer -- Treatment | en_GB |
dc.subject | Phosphoprotein phosphatases -- Inhibitors | en_GB |
dc.subject | Protein phosphatase 2 | en_GB |
dc.subject | Biochemical markers -- Diagnostic use | en_GB |
dc.title | Biomarkers predicting sensitivity to PP2A activation therapy in cancer | en_GB |
dc.type | patent | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
File | Description | Size | Format | |
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Patent_WO2018172419A1.pdf | 901.76 kB | Adobe PDF | View/Open |
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