Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/108993| Title: | An RNA based method to determine HER2 expression status in breast cancer patients |
| Authors: | Baldacchino, Shawn Falzon, Sharon Saliba, Christian Sacco, Keith DeGaetano, James Scerri, Christian Grech, Godfrey |
| Keywords: | Breast -- Cancer -- Immunotherapy Breast -- Cancer -- Treatment Epidermal growth factor Genes, erbB-2 M HER-2 gene |
| Issue Date: | 2015 |
| Publisher: | Foundation St.Gallen Oncology Conferences |
| Citation: | Baldacchino, S., Falzon, S., Saliba, C., Sacco, K., DeGaetano, J., Scerri, C., & Grech, G. (2015). An RNA based method to determine HER2 expression status in Breast Cancer Patients. 14th St. Gallen International Breast Cancer Conference, Vienna, Austria. |
| Abstract: | Introduction & Aim: Guidelines for the diagnostic evaluation of Human Epidermal Growth Factor Receptor 2 (HER 2) have been recently revised in the attempt to reduce inter laboratory variability and accuracy of the currently approved methods: In situ hybridisation ( and Immunohistochemistry (IHC)(Wolff et al 2013). Technical and subjective limitations persist in the determination of HER 2 overexpression ( Ballinger, Sanders, Abramson, 2014). This pilot study determined HER 2 expression in cell lines and Formalin Fixed Paraffin Embedded (FFPE) tissue lysates using an RNA based method developed on Luminex technology using the Affymetrix Quantigene 2.0 system. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/108993 |
| Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| An RNA based method to determine HER2 expression status in breast cancer patients 2015.pdf | 411.9 kB | Adobe PDF | View/Open |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.