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DC Field | Value | Language |
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dc.contributor.author | Grech, Godfrey | - |
dc.contributor.author | Abdul Aziz, A. | - |
dc.contributor.author | Lindern, Marieke von | - |
dc.date.accessioned | 2023-04-27T12:04:32Z | - |
dc.date.available | 2023-04-27T12:04:32Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Grech, G., & Abdul-Aziz, A., & von Lindern, M. (2012). The potential role of the homeobox gene, Hhex in haematopoietic progenitor expansion. VIII Malta Medical School Conference abstract book, P4.01. | en_GB |
dc.identifier.issn | 18133339 | - |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/109022 | - |
dc.description.abstract | Background: The decision of an erythroid progenitor to proliferate or differentiate is regulated at the level of (i) transcription; (ii) recruitment of transcripts to polysomes for protein synthesis and (iii) signal transduction activating functional effectors. We utilized a factor sensitive erythroid progenitor cell model to study the gene expression profile of cells under proliferative signals. We have shown previously that translation control is an extremely important level of regulation that controls the balance between proliferation and differentiation of erythroid progenitors. This led us to investigate those transcripts that are shifted to polysomes in cells stimulated by erythropoietin (Epo) or stem cell factor (SCF). | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | University of Malta. Medical School | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Homeobox genes | en_GB |
dc.subject | Erythroid precursor cells | en_GB |
dc.subject | Cell differentiation -- Molecular aspects | en_GB |
dc.subject | Cell proliferation -- Molecular aspects | en_GB |
dc.subject | Hematopoietic growth factors | en_GB |
dc.title | The potential role of the homeobox gene, Hhex in haematopoietic progenitor expansion | en_GB |
dc.type | conferenceObject | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.bibliographicCitation.conferencename | Eighth Malta Medical School Conference | en_GB |
dc.bibliographicCitation.conferenceplace | St. Julians, Malta. 29/11-01/12/2012. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | Malta Medical Journal | en_GB |
Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
File | Description | Size | Format | |
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The potential role of the homeobox gene Hhex in haematopoietic progenitor expansion 2012.pdf | 124.76 kB | Adobe PDF | View/Open |
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