Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/110215
Title: An analysis of blood parameter changes in Cushing's syndrome - a population-based study
Authors: Mangion, Jessica
Giordano Imbroll, Miriam
Craus, Sarah
Vassallo, Josanne
Gruppetta, Mark
Keywords: Cushing Syndrome -- Diagnosis
Blood cell count
Endocrine glands -- Diseases -- Epidemiology
Endocrine glands -- Diseases -- Malta -- Case studies
Glucocorticoids -- Physiological effect
Issue Date: 2022
Publisher: Bioscientifica
Citation: Mangion, J., Giordano Imbroll, M., Craus, S., Vassallo, J., & Gruppetta, M. (2022). An analysis of blood parameter changes in Cushing's syndrome - a population-based study. Endocrine Abstracts, 81, EP593.
Abstract: Aim: Glucocorticoids play a significant role in inflammation and immune system disruption. Our study aimed to analyse different biochemical and blood count indices and serum inflammationbased scores in patients with all different causes of endogenous Cushing’s Syndrome (CS) in a welldefined population.
Methods: Clinical records of 35 patients diagnosed with CS between 2008 and 2020 at the only central national health service hospital in Malta, were retrospectively analysed. Detailed clinical and biochemical data were obtained for each patient. Correlation and receiver operator characteristics (ROC) curve analyses were used to establish a threshold value for different variables to predict malignant CS.
URI: https://www.um.edu.mt/library/oar/handle/123456789/110215
Appears in Collections:Scholarly Works - FacM&SMed

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