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https://www.um.edu.mt/library/oar/handle/123456789/115224
Title: | Score reproducibility and reliability in differentiating small bowel subepithelial masses from innocent bulges |
Authors: | Sciberras, Martina Conti, Kelly Elli, Luca Scaramella, Lucia Riccioni, Maria Elena Marmo, Clelia Cadoni, Sergio McAlindon, Mark Sidhu, Reena O'hara, Fintan McNamara, Deirdre Rondonotti, Emanuele Piccirelli, Stefania Spada, Cristiano Bruno, Mauro Keuchel, Martin Baltes, Peter Calleja, Neville Cortegoso Valdivia, Pablo de'Angelis, Gian Luigi Margalit-Yehuda, Reuma Koulaouzidis, Anastasios Dray, Xavier Ellul, Pierre |
Authors: | International CApsule endoscopy REsearch (I-CARE) Group |
Keywords: | Capsule endoscopy Intestine, Small -- Diseases Gastrointestinal system -- Examination |
Issue Date: | 2022 |
Publisher: | Elsevier Inc. |
Citation: | Sciberras, M., Conti, K., Elli, L., Scaramella, L., Riccioni, M. E., Marmo, C., ... & endoscopy REsearch, I. C. (2022). Score reproducibility and reliability in differentiating small bowel subepithelial masses from innocent bulges. Digestive and Liver Disease, 54(10), 1403-1409. |
Abstract: | Aims: The primary aim of this study was to assess the reliability, intra- and inter-observer variation of the SPICE, Mucosal protrusion angle (MPA) and SHYUNG scores in differentiating a subepithelial mass (SEM) from a bulge. Methods: This retrospective multicentre study analysed the 3 scores, radiological studies, enteroscopy and/or surgical findings. Results: 100 patients with a potential SEM (mean age 57.6years) were recruited with 75 patients having pathology. In patients with a SEM the mean SPICE score was 2.04 (95% CI 1.82–2.26) as compared to 1.16 (95% CI 0.81–1.51) without any pathology (AUC 0.74, p<0.001), with a fair intra-observer agreement (Kappa 0.3, p<0.001) and slight interobserver agreement (Kappa 0.14, p<0.05). SPICE had a 37.3% sensitivity and 92.0% specificity in distinguishing between a SEM and bulge, whereas MPA<90˚ had 58.7% and 76.0% respectively, with poor intra-observer(p = 0.05) and interobserver agreement (p = 0.64). The SHYUNG demonstrated a moderate intra-observer (Kappa 0.44, p<0.001) and slight inter-observer reliability (Kappa 0.18, p<0.001). The sensitivity of an elevated SHYUNG score (≥4) in identifying a SEM was 18.7% with a specificity of 92.0% (AUC 0.71, p = 0.002). Conclusions: Though these scores are easy to use, they have, at best, slight to moderate intra and inter-observer agreement. Their overall diagnostic performances are limited. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/115224 |
Appears in Collections: | Scholarly Works - FacM&SPH |
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