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DC Field | Value | Language |
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dc.contributor.author | Chetcuti Zammit, Stefania | - |
dc.contributor.author | Schembri, John | - |
dc.contributor.author | Pisani, Anthea | - |
dc.contributor.author | Vella, Sarah | - |
dc.contributor.author | Azzopardi, Matthias | - |
dc.contributor.author | Skamnelos, Alexandros | - |
dc.contributor.author | Christodoulou, Dimitrios K. | - |
dc.contributor.author | Katsanos, Konstantinos H. | - |
dc.contributor.author | Ellul, Pierre | - |
dc.date.accessioned | 2024-03-27T14:02:49Z | - |
dc.date.available | 2024-03-27T14:02:49Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Chetcuti Zammit, S., Schembri, J., Pisani, A., Vella, S., Azzopardi, M., Skamnelos, A., ... & Ellul, P. (2018). Vitamin D and ulcerative colitis: is there a relationship with disease extent? Digestive Diseases, 37(3), 208-213. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/120350 | - |
dc.description.abstract | Introduction: Patients with ulcerative colitis (UC) can suffer from low serum vitamin D that can result in complications such as low bone mineral density. It can also reflect underlying disease severity. | en_GB |
dc.description.abstract | Methods: One hundred and ninety-seven patients previously diagnosed with UC from 2 European centers were prospectively recruited through the out-patient clinics. Clinical features (Montreal Classification, age, gender, previous and current medications, surgery), disease activity (Simple Clinical Colitis Activity Index [SCCAI]), blood investigations including serum inflammatory markers, and serum vitamin D were analyzed. The vitamin D levels were compared to a group of age- and gender-matched healthy controls. | en_GB |
dc.description.abstract | Results: Mean vitamin D levels were lower in patients with UC (54.6 nmol/L) than in controls (80.7 nmol/L; p = 0.0001). Mean vitamin D levels was lowest in patients with extensive UC (E3; p = 0.0001). Serum vitamin D was not significantly different across treatment groups (p = 0.876). There was no statistical difference in vitamin D levels across patients receiving calcium and vitamin D supplements (p =0.35) and there was no statistical correlation with SCCAI (p = 0.22). | en_GB |
dc.description.abstract | Conclusions: This study confirms the existence of low serum vitamin D in patients with UC when compared to healthy controls. It also provides evidence of an existing relationship between disease extent and serum vitamin D. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | S. Karger AG | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Inflammatory bowel diseases | en_GB |
dc.subject | Crohn's disease | en_GB |
dc.subject | Ulcerative colitis | en_GB |
dc.subject | Vitamin D | en_GB |
dc.title | Vitamin D and ulcerative colitis : is there a relationship with disease extent? | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.identifier.doi | 10.1159/000494439 | - |
dc.publication.title | Digestive Diseases | en_GB |
Appears in Collections: | Scholarly Works - FacM&SMed |
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