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https://www.um.edu.mt/library/oar/handle/123456789/122924| Title: | Erythroleukaemia, diabetes insipidus and hypophyseal damage : two case reports |
| Authors: | Piccin, A. Raimondi, R. Laspina, Stefan Marchi, M. Rodeghiero, F. Rovigatti, U. |
| Keywords: | Sella turcica Magnetic resonance imaging Hypothalamo-hypophyseal system Pituitary gland |
| Issue Date: | 2007 |
| Publisher: | Elsevier Ltd |
| Citation: | Piccin, A., Raimondi, R., Laspina, S., Marchi, M., Rodeghiero, F., & Rovigatti, U. (2007). Erythroleukaemia, diabetes insipidus and hypophyseal damage: Two case reports. Leukemia research, 31(8), 1135-1139. |
| Abstract: | We report on two cases of patients who developed diabetes insipidus (DI) before acute erythroleukaemia (EL). A brain MRI showed an empty sella turcica in one case and hypothalamo-hypophyseal peduncle damage in the second case. Reduced levels of TGF-1 and Vitamin D3, with associated EVI-1 over-expression and karyotypic abnormalities were documented. These two cases show specific chromosomal/molecular alterations in EL with DI. The hypothesis of pituitary involvement in erythroleukemogenesis is discussed. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/122924 |
| ISSN: | 10.1016/j.leukres.2006.11.008 |
| Appears in Collections: | Scholarly Works - FacM&SPat |
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|---|---|---|---|---|
| Erythroleukaemia_diabetes_insipidus_and_hypophyseal_damage_two_case_reports_2007.pdf Restricted Access | 992.95 kB | Adobe PDF | View/Open Request a copy |
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