Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/125180
Title: Interstitial lung disease secondary to oxaliplatin-raltitrexed based chemotherapy
Authors: Gauci, Luca
Scerri, Claudia
Mifsud, Maria
Gauci, Jonathan
Keywords: Interstitial lung diseases
Oxaliplatin
Drugs -- Side effect
Chemotherapy
Issue Date: 2024
Publisher: University of Malta. Medical School
Citation: Gauci, L., Scerri, C., Mifsud, M., & Gauci, J. (2024). Interstitial lung disease secondary to oxaliplatin-raltitrexed based chemotherapy. Malta Medical Journal, 36(3), 73-77.
Abstract: FOLFOX is a widely used regimen in the management of gastrointestinal malignancies and is a combination of 5-fluorouracil (5-FU), folinic acid, and oxaliplatin. Raltitrexed is an antifolate thymidylate synthase inhibitor which is used as an alternative when 5-FU is not tolerated. Here we present a case of interstitial lung disease as a rare side-effect of oxaliplatin and raltitrexed. Not much is known about the pathophysiology of the condition and most information available in the literature is taken from published case reports.
URI: https://www.um.edu.mt/library/oar/handle/123456789/125180
Appears in Collections:MMJ, Volume 36, Issue 3

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