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Title: | Trophoblastic disease and choriocarcinoma |
Authors: | Camilleri, Graziella Calleja-Agius, Jean Said, Edith |
Keywords: | Gestational trophoblastic disease Choriocarcinoma Molar pregnancy Tumors Chemotherapy Epigenetics |
Issue Date: | 2024 |
Publisher: | Elsevier |
Citation: | Camilleri, G., Calleja-Aguis, J., & Said, E. (2024). Trophoblastic disease and choriocarcinoma. European Journal of Surgical Oncology, 1-23. |
Abstract: | Gestational trophoblastic disease (GTD) is a group of diseases associated with 8 pregnancies that demonstrate abnormal development of trophoblastic cells. GTD includes 9 hydatidiform moles(HM) that may continue to further develop into gestational trophoblastic 10 neoplasms (GTN), such as choriocarcinoma (CC). Gestational CC is a malignant mass 11 development that may arise from HM, from other (normal) pregnancies or from other 12 gestational events (such as ectopic pregnancies). The aim of this review is to outline current 13 understating of the genetics and epigenetics of GTD and gestational CC and the link between 14 the two diseases. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/127213 |
ISSN: | 15322157 |
Appears in Collections: | Scholarly Works - FacM&SAna |
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