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dc.contributor.authorJakimovska Stefanovska, Marina-
dc.contributor.authorCelebic, Aleksandar-
dc.contributor.authorCalleja-Agius, Jean-
dc.contributor.authorDrusany Staric, Kristina-
dc.date.accessioned2024-11-07T09:15:53Z-
dc.date.available2024-11-07T09:15:53Z-
dc.date.issued2024-
dc.identifier.citationStefanovska, M. J., Celebic, A., Calleja-Agius, J., & Staric, K. D. (2024). Ovarian Cancer in Children and Adolescents: A Unique Clinical Challenge. European Journal of Surgical Oncology, 108785.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/128489-
dc.description.abstractOvarian cancer in children and adolescents is rare, presenting unique diagnostic and management challenges distinct from adult cases. This paper provides a comprehensive overview of this disease, focusing on the importance of a multidisciplinary approach to care. We discuss the common presentation of ovarian malignant masses in young patients, highlighting the role of imaging and tumor markers in diagnosis. The paper delves into the surgical management of these tumors, emphasizing the importance of fertility-sparing techniques whenever possible. We explore the role of adjuvant chemotherapy, considering histological subtypes and disease stage. Furthermore, we address the good prognosis associated with early diagnosis and treatment, with survival rates exceeding 90 % in many cases. Finally, the need for long-term follow-up to monitor for potential recurrence is underscored and the long-term treatment-related effects are addressed. This review aims to guide clinicians in providing optimal care for this unique patient population, emphasizing the importance of balancing oncological control with the preservation of future fertility and quality of life.en_GB
dc.language.isoenen_GB
dc.publisherElsevier Ltd.en_GB
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_GB
dc.subjectTeratomaen_GB
dc.subjectGerm cells -- Tumorsen_GB
dc.subjectOvaries -- Canceren_GB
dc.subjectSurgery -- Case studiesen_GB
dc.titleOvarian cancer in children and adolescents : a unique clinical challengeen_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holderen_GB
dc.description.reviewedpeer-revieweden_GB
dc.identifier.doi10.1016/j.ejso.2024.108785-
dc.publication.titleEuropean Journal of Surgical Oncologyen_GB
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