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https://www.um.edu.mt/library/oar/handle/123456789/130916| Title: | Differential expression of discriminative markers in matched invasion fronts and tumour buds in CRC |
| Other Titles: | 47P Differential expression of discriminative markers in matched invasion fronts and tumour buds in CRC |
| Authors: | Grech, Laura Debattista, Jessica Pisani, D. Grech, Godfrey |
| Keywords: | Colon (Anatomy) -- Cancer -- Prognosis Tumor markers -- Analysis Tumors -- Classification Gene expression -- Data processing |
| Issue Date: | 2023 |
| Publisher: | Elsevier BV |
| Citation: | Grech, L., Debattista, J., Pisani, D., & Grech, G. (2023). 47P Differential expression of discriminative markers in matched invasion fronts and tumour buds in CRC. ESMO Open, 8(1), doi: 10.1016/j.esmoop.2023.101857 |
| Abstract: | Background: In CRC molecular studies have shown that there is a great inter-tumour heterogeneity (ITH) within each UICC TNM stage and therefore a range of other transcriptional and protein biomarkers need to be investigated independently of the UICC TNM staging. In CRC, one of these adverse prognostic factors is tumour budding, Typically, tumour budding is assessed using H&E-stained specimens but scoring methods and grading schemes vary widely. A retrospective study was carried out to study the differential expression of discriminative markers in matched invasion fronts and tumour buds of 44 patients with stage 3/4 CRC disease. [excerpt] |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/130916 |
| Appears in Collections: | Scholarly Works - FacM&SPat |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Differential expression of discriminative markers in matched invasion fronts and tumour buds in CRC 2023.pdf | 58.31 kB | Adobe PDF | View/Open |
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