Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/13309
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dc.contributor.authorForte, John Stephen-
dc.date.accessioned2016-10-21T08:58:41Z-
dc.date.available2016-10-21T08:58:41Z-
dc.date.issued2001-
dc.identifier.citationForte, J. S. (2001). Interactions of grapefruit juice with drugs. The Chronic*ill, 5, 7-11.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar//handle/123456789/13309-
dc.description.abstractInteractions between grapefruit juice and oral drugs have been reported in the literature. The constituents of the juice that give rise to pharmacokinetic interactions have not been identified with certainty. It has been suggested that the mechanisms may involve inhibition of intestinal cytochrome P450 CYP3A4 isozyme and of drug efflux transporters. There are several variables that may influence the clinical significance of the drug-food interactions. In the pharmacy practice setting, the major concern is the increased bioavailability of drugs having a narrow therapeutic index.en_GB
dc.language.isoenen_GB
dc.publisherMalta College of Pharmacy Practiceen_GB
dc.rightsinfo:eu-repo/semantics/openAccessen_GB
dc.subjectDrug-nutrient interactionsen_GB
dc.subjectGrapefruit juiceen_GB
dc.subjectDrugs -- Metabolismen_GB
dc.titleInteractions of grapefruit juice with drugsen_GB
dc.typearticleen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.description.reviewedpeer-revieweden_GB
dc.publication.titleThe Chronic*ill-
Appears in Collections:JMCPP, Issue 5
JMCPP, Issue 5

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