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DC Field | Value | Language |
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dc.contributor.author | Cortes-Ramirez, Dionisio Alejandro | |
dc.contributor.author | Gainza-Cirauqui, Maria Luisa | |
dc.contributor.author | Echebarria-Goikouria, Maria-Angeles | |
dc.contributor.author | Aguirre-Urizar, Jose Manuel | |
dc.date.accessioned | 2017-02-06T12:48:52Z | |
dc.date.available | 2017-02-06T12:48:52Z | |
dc.date.issued | 2009 | |
dc.identifier.citation | Cortés-Ramírez, D.A., Gainza-Cirauqui, M.L., Echebarria-Goikouria, M.A., & Aguirre-Urizar, J.M. (2009). Oral lichenoid disease as a premalignant condition: the controversies and the unknown. Med Oral Patol Oral Cir Bucal, 14(3), E118-22. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar//handle/123456789/16301 | |
dc.description.abstract | We grouped as oral lichenoid disease (OLD) a series of chronic inflammatory processes with autoimmune base that affect the epithelium of the oral mucosa. This disease presents in 2% of the population with a marked predilection for the female gender, especially perimenopausal women. Clinically, it is characterized by the presence of lineal reticular papules and histologically by liquefaction degeneration of the basal layer of the epithelium associated with an inflammatory infiltrate with a "band-like" disposition on the lamina propria, composed primarily of T lymphocyte cells. Its pathogenicity is associated with deregulation of the cellular immune system, where the activated cytotoxic CD8 and the CD4 T helper lymphocytes induce apoptosis of the epithelial cells. Classically it has been considered a precancerous condition, although the malignant transformation does not exceed 1% of cases. In recent years the differentiation between oral lichen planus (OLP) and oral lichenoid lesions (OLL) has become important, since the latter might have a greater malignant potential. In this paper, we analyse and update some controversial aspects of this frequent oral disease in relation to the diagnosis and malignant potential. | en_GB |
dc.language.iso | en | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Lichen Planus, Oral | en_GB |
dc.subject | Mouth -- Diseases -- Diagnosis | en_GB |
dc.subject | Precancerous conditions | en_GB |
dc.subject | Diseases -- Causes and theories of causation | en_GB |
dc.title | Oral lichenoid disease as a premalignant condition : the controversies and the unknown | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
Appears in Collections: | Scholarly Works - FacDenDS |
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File | Description | Size | Format | |
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Oral lichenoid disease as a premalignant condition.pdf | 321.77 kB | Adobe PDF | View/Open |
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