Tardive dyskinesia II : treatment aspects, case report

Abstract

Tardive dyskinesia is a late side-effect of neuroleptic therapy which occurs in up to a fifth of chronic psychiatric patients treated with this group of drugs. Effective methods of treatment could reduce morbidity in a potentially large number of patients. Difficulties in the assessment of the efficacy of treatment methods could arise because it may be difficult to measure changes in tardive dyskinesia reliably. There is no well-established, safe and effective treatment for this syndrome. A case report illustrates the response of a severe phenothiazine induced dyskinesia to thiopropazate.