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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Attard, Everaldo | |
| dc.contributor.author | Scicluna-Spiteri, Anthony | |
| dc.contributor.author | Grixti, Mario | |
| dc.contributor.author | Cuschieri, Alfred | |
| dc.date.accessioned | 2017-06-13T09:39:25Z | |
| dc.date.available | 2017-06-13T09:39:25Z | |
| dc.date.issued | 1996-07-01 | |
| dc.identifier.citation | Attard, E., Scicluna-Spiteri, A., Grixti, M., & Cuschieri, A. (1996). The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro: A comparative study. Xjenza, 1(1), 29-34. | en_GB |
| dc.identifier.uri | https://www.um.edu.mt/library/oar//handle/123456789/19821 | |
| dc.description.abstract | A comparative study of the cytotoxicity of cucurbitacin E, a natural product, and busulphan on human ovarian and stomach cell lines was carried out. The cells were exposed to different concentrations of these two compounds and cell viability was determined from day 0 to day 11. It was observed that cucurbitacin E had a marked effect on the ovarian cancer cell line while busulphan showed a similar effect when exposed to the stomach cancer cell line. The drug-cell combinations showed a pronounced cell kill exponential curve, leading to the conclusion that cucurbitacin E exerts its pinocytic activity on the ovarian cancer cells while busulphan exerts its alkylating effect on the stomach cancer cells. | en_GB |
| dc.language.iso | en | en_GB |
| dc.publisher | Malta Chamber of Scientists | en_GB |
| dc.rights | info:eu-repo/semantics/openAccess | en_GB |
| dc.subject | Cucurbitaceae | en_GB |
| dc.subject | Stomach -- Cancer | en_GB |
| dc.subject | Ovaries -- Cancer | en_GB |
| dc.subject | Cell lines | en_GB |
| dc.title | The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro : a comparative study | en_GB |
| dc.type | article | en_GB |
| dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
| dc.description.reviewed | peer-reviewed | en_GB |
| Appears in Collections: | Scholarly Works - FacEMAPP Scholarly Works - InsESRSF | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| The_Cytotoxic_Activity_of_Cucurbitacin_E.pdf | 892.7 kB | Adobe PDF | View/Open |
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