Effect of Flunitrazepam : Atracurium administration on the pressor response to laryngoscopy and tracheal intubation

Abstract

The pressor response to direct laryngoscopy and endotracheal intubation was recognized by many investigators (Burstein et al. )(1), (Stoelting et al. )(2). The transitory nature of hypertension and tachycardia are probably of no consequence in healthy individuals, but may be hazardous in those patients suffering from cardiovascular diseases (Katz and Briggerl(3). Attempts to attenuate this pressor response were not satisfactory either because the reflex was incompletely blocked or the agent used may be too long acting and sometimes causes undesirable side effects (King et al. )(41 • The aim of the present study is to evaluate the pressor response to laryngoscopy and tracheal intubation following anaesthetic induction using Flunitrazipam Atracurium sequence and comparing the results with the commonly used Thiopentone- Suxamethonium one.