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https://www.um.edu.mt/library/oar/handle/123456789/24679| Title: | Three-component process for the synthesis of 2-amino-2-chromenes in aqueous media |
| Authors: | Ballini, Roberto Bosica, Giovanna Conforti, Maria Lina Maggi, Raimondo Mazzacani, Alessandro Righi, Paolo Sartori, Giovanni |
| Keywords: | Asymmetric synthesis Chemistry, Analytic |
| Issue Date: | 2001 |
| Publisher: | Pergamon Press |
| Citation: | Ballini, R., Bosica, G., Conforti, M. L., Maggi, R., Mazzacani, A., Righi, P., & Sartori, G. (2001). Three-component process for the synthesis of 2-amino-2-chromenes in aqueous media. Tetrahedron, 57(7), 1395-1398. |
| Abstract: | The reaction of an aldehyde, malononitrile and a phenol in water at reflux in the presence of cetyltrimethylammonium chloride (CTACl) as catalyst affords a one-pot synthesis of 2-amino-2-chromenes. Substituted 2-amino-2-chromenes 6 are synthesised in good yield and excellent selectivities by a three-component reaction between aldehydes 1, malononitrile 2 and phenols 4 in the presence of cetyltrimethylammonium chloride (CTACl) in water. |
| URI: | https://www.um.edu.mt/library/oar//handle/123456789/24679 |
| Appears in Collections: | Scholarly Works - FacSciChe |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| ballini2001 (6).pdf Restricted Access | 89.03 kB | Adobe PDF | View/Open Request a copy |
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