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https://www.um.edu.mt/library/oar/handle/123456789/24681
Title: | Uncatalyzed, green aza-Michael addition of amines to dimethyl maleate |
Authors: | Bosica, Giovanna Debono, Anthony John |
Keywords: | Catalyst poisoning Solvent wastes Solvents Aza compounds |
Issue Date: | 2014 |
Publisher: | Pergamon Press |
Citation: | Bosica, G., & Debono, A. J. (2014). Uncatalyzed, green aza-Michael addition of amines to dimethyl maleate. Tetrahedron, 70(37), 6607-6612. |
Abstract: | Dimethyl maleate was found to be a very reactive and selective acceptor for the aza-Michael addition in comparison to other commonly used electron-deficient alkenes. It reacts efficiently with a variety of aliphatic amines in complete absence of any catalyst and solvent at room temperature. Under these environmentally-friendly conditions, high yields of selectively mono-adducts were obtained within short reaction times. |
URI: | https://www.um.edu.mt/library/oar//handle/123456789/24681 |
Appears in Collections: | Scholarly Works - FacSciChe |
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File | Description | Size | Format | |
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1-s2.0-S0040402014009983-main.pdf Restricted Access | 563.87 kB | Adobe PDF | View/Open Request a copy |
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