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Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/25237
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dc.date.accessioned2018-01-02T10:04:35Z-
dc.date.available2018-01-02T10:04:35Z-
dc.date.issued2015-06-
dc.identifier.citationGrech, G., & Baldacchino, S. (2015). Molecular classification of breast cancer using quantigene plex 2.0 assay. Tumor profiling workshop in conjunction with the Postgraduate School Molecular Medicine, Erasmus MC, Affymetrics Seminar.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar//handle/123456789/25237-
dc.description.abstractUtilisation of biomarker panels is increasingly being employed to subtype tumours into therapeutic groups. This is exemplified by the oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) molecular classification in breast cancer. Understanding deregulated cellular mechanisms in tumours uncovers new targets for therapy, and defining biomarkers is vital for translation of basic research to the clinical setting. In silico analysis of datasets (cBioPortal) show that 60% of basal breast tumour patients exhibit deregulation of the phosphatase PP2A cellular feedback mechanism that regulates proliferation, differentiation and cell survival.en_GB
dc.language.isoenen_GB
dc.publisherUniversity of Malta. Department of Pathologyen_GB
dc.rightsinfo:eu-repo/semantics/openAccessen_GB
dc.subjectBreast -- Cancer -- Classificationen_GB
dc.subjectPhosphoprotein phosphatasesen_GB
dc.subjectBiomarkersen_GB
dc.titleMolecular classification of breast cancer using quantigene plex 2.0 assayen_GB
dc.typepresentationen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.description.reviewedN/Aen_GB
dc.contributor.creatorGrech, Godfrey-
dc.contributor.creatorBaldacchino, Shawn-
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