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Title: | Activation of nicotinic cholinergic receptors modifies the processing of rat hippocampal amyloid precursor protein both in vivo and in vitro |
Authors: | Scerri, Charles |
Keywords: | Rats as laboratory animals Alpha7 nicotinic acetylcholine receptor Amyloid beta-protein precursor |
Issue Date: | 2011 |
Publisher: | Elsevier Inc. |
Citation: | Scerri, C. (2011). Activation of nicotinic cholinergic receptors modifies the processing of rat hippocampal amyloid precursor protein both in vivo and in vitro. Alzheimer's & Dementia, 7(4), 581. |
Abstract: | Previous studies have shown that stimulation of nicotinic acetylcholine receptors (nAChRs) enhances the expression and secretion of amyloid precursor protein (APP) in various cell lines. Using complementary in vivo and in vitro experiments, this study investigated the extent to which nicotine administration influences APP levels and processing in the rat brain. |
URI: | https://www.um.edu.mt/library/oar//handle/123456789/27745 |
Appears in Collections: | Scholarly Works - FacM&SPat |
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