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https://www.um.edu.mt/library/oar/handle/123456789/28897| Title: | Mendelian randomization in inflammatory conditions - the exception rather than the rule? |
| Authors: | Bezzina Wettinger, Stephanie Doggen, C. Spek, A. Rosendaal, F. R. Reitsma, P. H. Spek, A. Felice, Alex |
| Keywords: | Inflammation RNA Myocardial infarction |
| Issue Date: | 2014 |
| Publisher: | Elsevier |
| Citation: | Bezzina Wettinger, S., Doggen, C. J. M., Spek, A., Felice, A., Rosendaal, F. R., & Reitsma, P. H. (2014). Mendelian randomization in inflammatory conditions-the exception rather than the rule?. Atherosclerosis, 235(2), e221-e222. |
| Abstract: | Objectives: To assess causality of inflammatory RNA molecules for myocardial infarction (MI) using a Mendelian randomization approach. Methods: Samples were 524 men with a history of MI and 628 controls from the Study of Myocardial Infarction Leiden (SMILE). Macrophage migration inhibitory factor (MIF) G-173C, protein tyrosine phosphatase, non-receptor type, 1 (PTPN1) 1484InsG and chemokine (C-C motif) ligand 3 (CCL3 or MIP1-alpha) C1685T were selected since they are in genes that exhibited elevated mRNA expression measured using multiplex ligation probe-dependent amplification in cases compared to controls. |
| URI: | https://www.um.edu.mt/library/oar//handle/123456789/28897 |
| Appears in Collections: | Scholarly Works - FacM&SPB |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Mendelian_randomization_in_inflammatory_conditions_the_exception_rather_than_the_rule_2014.pdf Restricted Access | 71.02 kB | Adobe PDF | View/Open Request a copy |
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