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DC Field | Value | Language |
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dc.date.accessioned | 2019-11-20T12:52:49Z | - |
dc.date.available | 2019-11-20T12:52:49Z | - |
dc.date.issued | 2015-09 | - |
dc.identifier.citation | Sammut Bartolo, N., Mallia, C. D., Vella, J., Serracino Inglott, A., & Ferrito, V. (2015, September). Improving the yield in orthoesterification of steroids. Poster session presented at the FIP 75th World Congress of Pharmacy and Pharmaceutical Sciences, Düsseldorf, Germany. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/48811 | - |
dc.description.abstract | A poster presentation about improving the yield in orthoesterification of steroids. Introduction: Steroids are used to treat various conditions from asthma to skin inflammation. Orthoesterification of steroids at C17 and C21 leads to the formation of compounds which are more potent than their parent steroids. Steroid orthoesters are synthesized by reacting a selected steroid with the respective orthoester. The parent steroid should have two hydroxyl groups situated in close proximity to react with the orthoester, for example at C17 and C21. An acid is used to catalyse the reaction. Aims: To synthesise and improve the yield of the orthoesterification of a steroidal compound. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | University of Malta. Department of Pharmacy | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Steroids | en_GB |
dc.subject | Steroids -- Analysis | en_GB |
dc.subject | Tetrahydrofuran | en_GB |
dc.subject | Pyridinium compounds | en_GB |
dc.subject | Catalysis | en_GB |
dc.title | Improving the yield in orthoesterification of steroids | en_GB |
dc.type | presentation | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | N/A | en_GB |
dc.contributor.creator | Sammut Bartolo, Nicolette | - |
dc.contributor.creator | Mallia, Christopher D. | - |
dc.contributor.creator | Vella, Janis | - |
dc.contributor.creator | Serracino-Inglott, Anthony | - |
dc.contributor.creator | Ferrito, Victor | - |
Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
File | Description | Size | Format | |
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Improving_the_yield_in_orthoesterification_of_steroids_2015.pdf | 602.38 kB | Adobe PDF | View/Open |
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