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Title: | A qualitative and quantitative method for difluprednate using high performance liquid chromatography |
Authors: | Sammut Bartolo, Nicolette Vella, Janis Serracino-Inglott, Anthony Ferrito, Victor Azzopardi, Lilian M. |
Keywords: | Steroids -- Research High performance liquid chromatography Acetonitrile Steroids -- Synthesis |
Issue Date: | 2014-03 |
Publisher: | University of Malta. Department of Pharmacy |
Citation: | Sammut Bartolo, N., Vella, J., Serracino-Inglott, A., Ferrito, V., & Azzopardi, L. M. (2014, March). A qualitative and quantitative method for difluprednate using high performance liquid chromatography. Poster session presented at the World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Lisbon, Portugal. |
Abstract: | A poster presentation regarding a qualitative and quantitative method for difluprednate using high performance liquid chromatography. Introduction: Monitoring and determination of impurities during synthesis of active pharmaceutical ingredients (APIs), require the use of various analytical methods. Initially not all the chemical structures of impurities are known therefore various methods should be developed to allow the reliable distinction between one chemical structure from another. Since most of the impurities generated during a reaction are similar to the product, different compounds may co-elute, masking the presence of some impurities. Aims: To develop an analytical method, using HPLC, to detect and quantify difluprednate and the impurities produced during the synthesis of this steroid. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/49775 |
Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
File | Description | Size | Format | |
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A_qualitative_and_quantitative_method_for_difluprednate_using_high_performance_liquid_chromatography_2014.pdf | 381.73 kB | Adobe PDF | View/Open |
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