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https://www.um.edu.mt/library/oar/handle/123456789/49976
Title: | Pharmacist-led rapid point-of-care CYP2C19 genotyping for individualisation of antiplatelet therapy |
Authors: | Wirth, Francesca Xuereb, Robert G. Fenech, Albert Azzopardi, Lilian M. |
Keywords: | Blood platelet disorders Blood platelets -- Aggregation Clopidogrel Coronary arteries -- Stenosis Point-of-care testing Cytochrome P-450 CYP2C19 Pharmacists -- Practice |
Issue Date: | 2016-03 |
Publisher: | University of Malta. Department of Pharmacy |
Citation: | Wirth, F., Xuereb, R. G., Fenech, A., & Azzopardi, L. M. (2016, March). Pharmacist-led rapid point-of-care CYP2C19 genotyping for individualisation of antiplatelet therapy. Poster session presented at the 21st Congress of the European Association of Hospital Pharmacists, Vienna, Austria. |
Abstract: | A poster presentation regarding pharmacist-led rapid point-of-care CYP2C19 genotyping for individualisation of antiplatelet therapy. Background: Presence of the CYP2C19 loss-of-function (LoF) *2 allele is associated with reduced antiplatelet effect in clopidogrel-treated patients. Since about 50% of major adverse cardiac events occur within the first few days after percutaneous coronary intervention (PCI), a rapid CYP2C19*2 genotype result is important to individualise antiplatelet therapy at the start of treatment. Objective: To apply a pharmacist-led process to individualise antiplatelet therapy guided by CYP2C19*2 genotype using the novel rapid point-of-care (POC) genetic testing system in patients undergoing PCI. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/49976 |
Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
File | Description | Size | Format | |
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Pharmacist_led_rapid_point_of_care_CYP2C19_genotyping_for_individualisation_of_antiplatelet_therapy_2016.pdf | 383.35 kB | Adobe PDF | View/Open |
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