Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/51179
Title: | Analysis of amitriptyline and its metabolites |
Authors: | Mifsud Buhagiar, Luana Sammut Bartolo, Nicolette Vella Szijj, Janis Ferrito, Victor Serracino-Inglott, Anthony LaFerla, Godfrey |
Keywords: | Amitriptyline -- Analysis Metabolites -- Analysis Chromatographic analysis -- Methodology Cardiovascular toxicology |
Issue Date: | 2018-11 |
Publisher: | University of Malta. Department of Pharmacy |
Citation: | Mifsud Buhagiar, L., Sammut Bartolo, N., Vella Szijj, J., Ferrito, V., Serracino Inglott, A., & LaFerla, G. (2018, November). Analysis of amitriptyline and its metabolites. Poster session presented at the X Malta Medical School Conference, St Julian's, Malta. |
Abstract: | A poster presentation regarding the analysis of amitriptyline and its metabolites. Aims: Amitriptyline, a tricyclic antidepressant, has been renowned for over half a century for its efficacy, pharmacoeconomic benefits and potential adverse effects. Most analytical procedures utilised for recommended therapeutic drug monitoring only account for amitriptyline as the parent drug and nortriptyline as the active demethylated metabolite. This project aimed to determine the hydroxylated metabolites which may prove expedient due to possible clinical effects, particularly cardiovascular toxicity. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/51179 |
Appears in Collections: | Scholarly Works - FacM&SPha |
Files in This Item:
File | Description | Size | Format | |
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Analysis_of_amitriptyline_and_its_metabolites_2018.pdf | 621.84 kB | Adobe PDF | View/Open |
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