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Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/54126
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dc.date.accessioned2020-04-14T07:46:28Z-
dc.date.available2020-04-14T07:46:28Z-
dc.date.issued2017-
dc.identifier.citationMifsud Buhagiar, L., Grech, A., Casha, M., Serracino-Inglott, A., & LaFerla, G. (2017). The role of pharmacogenetics in rediscovering old drugs : spotlight on amitriptyline. Poster session presented at the ESPT Fourth Conference. Catania, Italy.en_GB
dc.identifier.urihttps://www.um.edu.mt/library/oar/handle/123456789/54126-
dc.description.abstractA poster presentation regarding the role of pharmacogenetics in rediscovering old drugs with a special spotlight on amitriptyline. Introduction: Tricyclic antidepressants (TCAs) are often overlooked in clinical practice on claims of poor tolerability, notwithstanding their potential advantages in efficacy and pharmacoeconomics. Most data available on TCAs derives from an era when genotyping studies were not available. While still being used in psychiatry, prescribing trends of amitriptyline are increasing in the context of pain management. The effect of CYP2D6 and CYP2C19 polymorphisms on individual amitriptyline and metabolites exposure may predispose to adverse events or treatment failure.en_GB
dc.language.isoenen_GB
dc.publisherUniversity of Malta. Department of Pharmacyen_GB
dc.rightsinfo:eu-repo/semantics/openAccessen_GB
dc.subjectPharmacogenetics -- Researchen_GB
dc.subjectDrugs -- Prescribingen_GB
dc.subjectPharmacogenetics -- Testingen_GB
dc.subjectPersonalized medicineen_GB
dc.subjectAntidepressantsen_GB
dc.titleThe role of pharmacogenetics in rediscovering old drugs : spotlight on amitriptylineen_GB
dc.typepresentationen_GB
dc.rights.holderThe copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.en_GB
dc.description.reviewedN/Aen_GB
dc.contributor.creatorMifsud Buhagiar, Luana-
dc.contributor.creatorGrech, Anton-
dc.contributor.creatorCasha, Marilyn-
dc.contributor.creatorSerracino-Inglott, Anthony-
dc.contributor.creatorLaFerla, Godfrey-
Appears in Collections:Scholarly Works - FacM&SPha

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