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https://www.um.edu.mt/library/oar/handle/123456789/55743
Title: | Broad-spectrum antibiotic use in Europe : more evidence of cultural influences on prescribing behaviour |
Authors: | Borg, Michael Angelo Camilleri, Liberato |
Keywords: | Antibiotics Antibiotics -- Mechanism of action Drugs -- Prescribing -- Europe Drugs -- Prescribing -- Cross-cultural studies |
Issue Date: | 2019 |
Publisher: | Oxford University Press |
Citation: | Borg, M. A., & Camilleri, L. (2019). Broad-spectrum antibiotic use in Europe: more evidence of cultural influences on prescribing behaviour. Journal of Antimicrobial Chemotherapy, 74(11), 3379-3383. |
Abstract: | Objectives: Sociocultural factors have been hypothesized as important drivers of inappropriate antibiotic prescribing in European ambulatory care. This study sought to assess whether they can also explain the reported variation in broad-spectrum antibiotic (Br-Ab) use among EU/European Economic Area (EEA) countries. Methods: Correlation and regression analysis were performed, using the bootstrap method, between Br-Ab ratios reported from 28 EU countries by the ECDC, and national Hofstede cultural dimensions and control of corruption (CoC) scores. Results: Significant bootstrapping correlation coefficients were identified between Br-Ab ratios and the dimension of uncertainty avoidance (UAI) as well as CoC. However, following both bootstrapping multiple regression and generalized linear modelling, only UAI was retained as the sole predictor. A logarithmic model explained 58.6% of the variation in European Br-Ab variability solely using national UAI scores (P,0.001). Conclusions: Br-Ab prescribing appears to be driven by the level of UAI within the country. Any interventions aimed at reducing Br-Ab in high-consuming EU/EEA countries need to address this cultural perception to maxi-mize their chances of success. |
URI: | https://www.um.edu.mt/library/oar/handle/123456789/55743 |
Appears in Collections: | Scholarly Works - FacSciSOR |
Files in This Item:
File | Description | Size | Format | |
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Broad spectrum antibiotic use in Europe. More evidence of cultural influences on prescribing behaviour.pdf | 197 kB | Adobe PDF | View/Open |
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