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https://www.um.edu.mt/library/oar/handle/123456789/59565Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Borg, Marika | - |
| dc.contributor.author | Calleja-Agius, Jean | - |
| dc.date.accessioned | 2020-08-18T09:07:43Z | - |
| dc.date.available | 2020-08-18T09:07:43Z | - |
| dc.date.issued | 2015 | - |
| dc.identifier.citation | Borg, M., & Calleja-Agius, J. (2015). The effect of cytokines on skin during menopause. In M. A. Farage, K. W. Miller, N. Fugate Woods & H. I. Maibach (Eds.), Skin, Mucosa and Menopause (pp. 53-70). Berlin: Springer. | en_GB |
| dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/59565 | - |
| dc.description.abstract | Skin cells produce a variety of cytokines that are involved in skin homeostasis. The decrease in estrogen level that occurs in menopause brings with it an imbalanced level of cytokines that causes several menopausal complications including cutaneous aging which, although not life-threatening, affects the well-being and quality of life of elderly women. An imbalance in the pro- and anti-inflammatory cytokines drives the aging process and brings about the appearance of old skin characteristics like dry wrinkled skin, delayed wound healing, easy bruising, body hair loss, and fine-textured scalp hair. TNF-α, IL-6, CCN1, and TGF-β are involved in collagen homeostasis, which affects skin thickness, skin wrinkling, and cutaneous wound healing. Other cytokines produced by epidermal or dermal cells that are involved in skin aging are IL-1, IL-8, IL-10, IL-18, and interferons. Further research is needed to establish the role of cytokines in the prevention and treatment of cutaneous aging. | en_GB |
| dc.language.iso | en | en_GB |
| dc.publisher | Springer | en_GB |
| dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
| dc.subject | Cytokines | en_GB |
| dc.subject | Menopause | en_GB |
| dc.subject | Skin -- Aging | en_GB |
| dc.title | The effect of cytokines on skin during menopause | en_GB |
| dc.title.alternative | Skin, Mucosa and Menopause | en_GB |
| dc.type | bookPart | en_GB |
| dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
| dc.description.reviewed | peer-reviewed | en_GB |
| dc.identifier.doi | 10.1007/978-3-662-44080-3_5 | - |
| Appears in Collections: | Scholarly Works - FacM&SAna | |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| The_effect_of_cytokines_on_skin_during_menopause_2015.pdf Restricted Access | 289.8 kB | Adobe PDF | View/Open Request a copy |
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