Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/59822
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Micallef, Sarah | - |
dc.contributor.author | Micallef, Darren | - |
dc.contributor.author | Schembri-Wismayer, Pierre | - |
dc.contributor.author | Brincat, Mark P. | - |
dc.contributor.author | Calleja-Agius, Jean | - |
dc.date.accessioned | 2020-08-25T09:27:42Z | - |
dc.date.available | 2020-08-25T09:27:42Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Micallef, S., Micallef, D., Schembri-Wismayer, P., Brincat, M. P., & Calleja-Agius, J. (2015). Chemoprevention of breast cancer among women at elevated risk as defined by Gail Score. Minerva Ginecologica, 67(4), 335-352. | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/59822 | - |
dc.description.abstract | The risk of an individual woman to develop breast cancer over a 5-year period can be estimated using the Gail Model. The risk factors included in this model effectively classify patients into two different subgroups. One subgroup comprises patients at increased risk because of increased exposure to estrogen. These women are more likely to benefit from endocrine chemopreventive therapies, namely selective estrogen receptor modulators (SERMs) and aromatase inhibitors (AIs). The second subgroup comprises women who have inherited genetic mutations that predispose them to breast cancer. Chemoprevention in these patients is more likely to be achieved by novel agents, such as lapatinib, gefitinib, fenretinide, rexinoids and poly(ADP-ribose) polymerase (PARP) -inhibitors. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | Edizioni Minerva Medica | en_GB |
dc.rights | info:eu-repo/semantics/restrictedAccess | en_GB |
dc.subject | Chemoprevention | en_GB |
dc.subject | Cancer -- Chemoprevention | en_GB |
dc.subject | Breast -- Cancer | en_GB |
dc.title | Chemoprevention of breast cancer among women at elevated risk as defined by Gail Score | en_GB |
dc.type | article | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder. | en_GB |
dc.description.reviewed | peer-reviewed | en_GB |
dc.publication.title | Minerva Ginecologica | en_GB |
Appears in Collections: | Scholarly Works - FacM&SAna |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Chemoprevention_of_breast_cancer_among_women_at_elevated_risk_as_defined_by_Gail_Score_2015.pdf Restricted Access | 986.91 kB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.