Please use this identifier to cite or link to this item: https://www.um.edu.mt/library/oar/handle/123456789/67070
Title: Small bowel perforation secondary to intestinal tuberculosis in patient with chronic idiopathic myelofibrosis
Authors: Shafi, Mohamed
Mohamad, Ikhwan Sani
Wan Mokhter, Wan Mokhzani
Merican, Siti Rahmah Hashim
Zakaria, Zaidi
Nik Min, Nik Fatin Amirah
Hussain, Faezahtul Arbaeyah
Keywords: Primary Myelofibrosis
Tuberculosis, Gastrointestinal
Intestine, Small -- Diseases
Issue Date: 2020-12
Publisher: University of Malta. Medical School
Citation: Shafi, M., Mohamad, I. S., Wan Mokhter, W. M., Merican, S. R. H., Zakaria, Z., Nik Min, N. F. A., & Hussain, F. A. (2020). Small bowel perforation secondary to intestinal tuberculosis in patient with chronic idiopathic myelofibrosis. Malta Medical Journal, 32(3), 107-112.
Abstract: Idiopathic myelofibrosis is a clonal hematopoetic stem cell disorder due to a mutation in the signaling regulator gene Janus Kinase 2 (JAK2).The condition is widely treated with Ruxolitinib which is a JAK2 inhibitor along with prednisolone. However, these treatment despite promising has been linked with the risk of opportunistic infections and reactivation of tuberculosis.We reported a patient with chronic idiopathic myelofibrosis who developed small bowel perforations secondary to flare up of gut tuberculosis. The perforation sites were resected and double barrel stoma was created.
URI: https://www.um.edu.mt/library/oar/handle/123456789/67070
Appears in Collections:MMJ, Volume 32, Issue 3
MMJ, Volume 32, Issue 3

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