Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/70946| Title: | Colistin in burn intensive care : back to the future? |
| Authors: | Azzopardi, Ernest A. Boyce, Dean Edward Thomas, David W. Dickson, William A. |
| Keywords: | Colistin -- Therapeutic use Gram-negative bacterial infections -- Chemotherapy Multidrug resistance -- Databases Antibacterial agents -- Evaluation Surgery, Operative Burns and scalds -- Treatment |
| Issue Date: | 2013 |
| Publisher: | Elsevier |
| Citation: | Azzopardi, E. A., Boyce, D. E., Thomas, D. W., & Dickson, W. A. (2013). Colistin in burn intensive care: back to the future?. Burns, 39(1), 7-15. |
| Abstract: | Colistin is a venerable antibiotic whose fortunes have been revived by its excellent activity, the diminishing output of novel clinically effective antibiotics and the increasing importance of MDR infection in burn surgery, both in the civilian and military arenas. This review synthesizes current evidence on the usage of colistin in burn surgery including the structure– activity relationship; dosing, pharmacokinetics/pharmacodynamic (PK/PD), analytic methods, resistance and current research efforts into the redevelopment of this antibiotic, to distil recommendations for future research and clinical efficacy. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/70946 |
| Appears in Collections: | Scholarly Works - FacM&SAna |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Colistin_in_burn_intensive_care_back_to_the_future_2013.pdf Restricted Access | 442.84 kB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.