Please use this identifier to cite or link to this item:
https://www.um.edu.mt/library/oar/handle/123456789/77240| Title: | Studies on the N-oxidation of heterocycles of pharmacological importance : the N-oxidation of indoles |
| Authors: | Felice, Maryanne (1977) |
| Keywords: | Heterocyclic compounds Indole Pharmacology |
| Issue Date: | 1977 |
| Citation: | Felice, M. (1977). Studies on the N-oxidation of heterocycles of pharmacological importance : the N-oxidation of indoles (Master’s dissertation). |
| Abstract: | Hepatic microsomal oxidation on the nitrogen on the indole ring has been investigated with 2-phenylindole as substrate. N-hydroxy-2-phenylindole has been isolated following incubation of different concentrations of substrate and co-enzymes with whole liver homogenates and microsomal preparations from rabbit and guinea-pig, with and without inducer pretreatment. The hydroxy metabolite has been shown to be identical with N-hydroxy-2-phenylindole, obtained by chemical synthesis, through its TLC and GC behaviour and its IR and NMR spectral characteristics |
| Description: | M.PHIL. |
| URI: | https://www.um.edu.mt/library/oar/handle/123456789/77240 |
| Appears in Collections: | Dissertations - FacM&S - 1972-1977 Dissertations - FacM&SPha - 1977-1995 |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| M.PHIL._Felice_Maryann_1977.pdf Restricted Access | 4.98 MB | Adobe PDF | View/Open Request a copy |
Items in OAR@UM are protected by copyright, with all rights reserved, unless otherwise indicated.