One pot aza-Friedel-Crafts multicomponent reaction under green chemistry conditions

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DC Field	Value	Language
dc.date.accessioned	2021-06-16T08:14:48Z	-
dc.date.available	2021-06-16T08:14:48Z	-
dc.date.issued	2017	-
dc.identifier.citation	Abdilla, R. (2017). One pot aza-Friedel-Crafts multicomponent reaction under green chemistry conditions (Master’s dissertation).	en_GB
dc.identifier.uri	https://www.um.edu.mt/library/oar/handle/123456789/77328	-
dc.description	M.SC.CHEMISTRY	en_GB
dc.description.abstract	Indole and its 3-substituted derivatives play crucial roles in various biological life forms and whilst some of them are naturally-occurring, others have been synthesized for their pharmaceutical capabilities. This study entailed synthesizing 3-substituted indoles via the one-pot multicomponent aza-Friedel-Crafts reactions, starting from a very wide range of aldehydes; primary, secondary and tertiary aromatic amines; and indoles. Following the principles of green chemistry, catalyst screening and condition optimization were performed on a model reaction. It was found that the reactions could be catalyzed by a heterogeneous, recyclable, easily and safely-prepared catalyst: silicotungstic acid supported on Amberlyst 15 beads.	en_GB
dc.language.iso	en	en_GB
dc.rights	info:eu-repo/semantics/restrictedAccess	en_GB
dc.subject	Green chemistry	en_GB
dc.subject	Indole	en_GB
dc.subject	Friedel-Crafts reaction	en_GB
dc.title	One pot aza-Friedel-Crafts multicomponent reaction under green chemistry conditions	en_GB
dc.type	masterThesis	en_GB
dc.rights.holder	The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder.	en_GB
dc.publisher.institution	University of Malta	en_GB
dc.publisher.department	Faculty of Science. Department of Chemistry	en_GB
dc.description.reviewed	N/A	en_GB
dc.contributor.creator	Abdilla, Roderick (2017)	-
Appears in Collections:	Dissertations - FacSci - 2017 Dissertations - FacSciChe - 2017

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