A correlation of physicochemical properties of selected medicinal compounds to their anatomical therapeutic chemical classification

Abstract

The Anatomical Therapeutic Chemical (ATC) classification system managed by the World Health Organisation is nowadays considered the most widely used drug classification system (Chen et al., 2012). Identification of rules defining classification at the molecular level as per the ATC classification system would prove beneficial for further medicinal substances development. Nevertheless, such studies are seldom found in the literature, and thus although mapping of ATC codes would provide beneficial information, the process is a challenging one (Wang et al., 2013). The aim of the study was to assess whether common physicochemical profiles exist for compounds classified within the same ATC sub-groups.