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DC Field | Value | Language |
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dc.date.accessioned | 2021-09-20T08:18:50Z | - |
dc.date.available | 2021-09-20T08:18:50Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Azzopardi, J. I., & Blundell, R. (2018). Review: the use of umbilical cord stem cells as a form of treatment. University of Malta. Department of Physiology and Biochemistry | en_GB |
dc.identifier.uri | https://www.um.edu.mt/library/oar/handle/123456789/81283 | - |
dc.description.abstract | Stem cells are a type of cells that can self-renew and undergo lineage differentiation – this is what is known as “developmental plasticity”. Once regarded as a waste product, the umbilical cord was found to be a good source of hematopoietic and mesenchymal stem cells in 1974, with the first successful transplantation occurring in 1988. The use of umbilical cord as a source of hematopoietic stem cells for transplantation has many advantages over other sources of haematopoietic stem cells, namely the bone marrow. Advantages include a larger amount of stem cells per unit volume, decreased risk of transmission of Epstein-Barr virus and cytomegalovirus infections, greater tolerance of Human Leukocyte Antigen (HLA) mismatches and the ability to be stored in a bank. In this review, we assessed the safety and efficacy of using umbilical cord blood-derived stem cells as treatment for different diseases by looking into some of the latest clinical cases. | en_GB |
dc.language.iso | en | en_GB |
dc.publisher | University of Malta. Department of Physiology and Biochemistry | en_GB |
dc.rights | info:eu-repo/semantics/openAccess | en_GB |
dc.subject | Stem cells | en_GB |
dc.subject | Embryonic stem cells | en_GB |
dc.subject | Adult stem cells | en_GB |
dc.subject | Umbilical cord | en_GB |
dc.title | Review : the use of umbilical cord stem cells as a form of treatment | en_GB |
dc.type | review | en_GB |
dc.rights.holder | The copyright of this work belongs to the author(s)/publisher. The rights of this work are as defined by the appropriate Copyright Legislation or as modified by any successive legislation. Users may access this work and can make use of the information contained in accordance with the Copyright Legislation provided that the author must be properly acknowledged. Further distribution or reproduction in any format is prohibited without the prior permission of the copyright holder | en_GB |
dc.description.reviewed | N/A | en_GB |
dc.identifier.doi | 10.13140/RG.2.2.20248.03845 | - |
dc.contributor.creator | Azzopardi, Joseph Ignatius | - |
dc.contributor.creator | Blundell, Renald | - |
Appears in Collections: | Scholarly Works - FacM&SPB |
Files in This Item:
File | Description | Size | Format | |
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Review.pdf | 192.48 kB | Adobe PDF | View/Open |
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